Strattera (Atomoxetine Hydrochloride)

Drug Info

• Brand Names: Strattera, Atomoxet, Concentin;
• Active Ingredient: Atomoxetine Hydrochloride;
• Manufacturer: Eli Lilly.

Strattera and its active ingredient Atomoxetine

ADHD is an imbalance of major neurotransmitters in the central nervous system - norepinephrine and dopamine. Strattera restores neurotransmitter imbalance, causing a positive effect on such brain functions as concentration, attention, feeling of pleasure, and behavior.

Usually, the effect is seen rapidly (within 7 - 21 days) after the start of treatment. Strattera is believed to increase stress resistance, improve memory, stimulate creativity, and help focus on completing specific tasks like studying and doing homework.

Indications for use

Strattera is prescribed and can be an important part of the treatment in the following cases:

• For ADHD in children over 6 years;
• For ADHD in adults, provided that the disorder's symptoms have already been present in childhood.

ADHD, as a neurobehavioral disorder, is the most common indication for using pills Strattera. The drug can help children over 6 years, young adults, and adults manage symptoms of the disorder, including inattention, incontinence, hyperactivity, and impulsivity.

It is essential to understand that the therapeutic effect may not be felt immediately but only in several weeks, less often after a few months. That is why one should not make hasty conclusions about the ineffectiveness of the pills at the start of the course.

Treatment regimens and dosages

Oral pills Strattera contain the main component Atomoxetine and is available in several dosages: 40 mg, 25 mg, 18 mg, and 10 mg. A variety of doses allows selecting the optimal option for adults and kids.

If Strattera is prescribed to you or your child, the treatment will start with a low dosage that may be gradually increased. Preferred dosage regimen:

• Usually, treatment in children begins with 0.5 mg/kg daily, then 0.8 mg/kg daily, increasing to 1.2 mg/kg daily, and keeping the maintenance dose at 1.2 mg/kg daily;
• 1.8 mg/kg dose per day should not be exceeded unless your doctor tells you otherwise.

Possible dosage regimen for children (over 40 kg) and adults:

• Usually, the initial dose is 40 mg per day, then it is increased to 80 mg per day with a further maintenance dose of 80 - 120 mg per day;
• 120 mg dose per day should not be exceeded unless your doctor tells you otherwise.

A disorder such as ADHD can be treated with Strattera and behavioral therapy. The treatment is usually prescribed by an expert like a pediatrician or psychiatrist; however, the state may be monitored by a general practitioner.

Recommendations for use

To get maximum effect from the treatment, follow these tips and recommendations:

• Do not miss taking the pills;
• The next dose should be taken at the same time daily;
• You can choose the time to take the pills: once per day (usually in the morning) or twice per day (in the morning and evening);
• Do not crush or chew the pills before taking them;
• Swallow whole pills before or after the meal.

In any case, follow the instructions for taking medications. Your doctor may withdraw treatment; it should be done gradually within 2 - 3 weeks.

Missed Dose

Skipped doses should be minimized for treatment to be effective. Avoid taking extra doses and other inaccuracies. If you missed taking the pill during the day, skip it, but remember to take the following dose on time.

Precautions

When using the medication, precautions must be taken:

• Remember that treatment starts with low doses that are gradually increased at one-week or longer intervals;
• The dose should be increased with caution for people with liver problems;
• Parents or other persons with parental responsibility must monitor a child’s behavior after the use of the pills, especially at the beginning of treatment;
• If you are concerned with slow growth or weight gain in a child with prolonged use of the pills, consult your doctor;
• Strattera may cause cardiovascular side effects. After starting the medication, you should monitor the impact of the drug on heart and blood pressure;
• The drug can cause aggression, fatigue, drowsiness, or fainting. Avoid operating dangerous machinery, driving, or working at height until you know what effect the medicine has.

Use of Strattera during pregnancy

The drugs containing Atomoxetine are not suitable during pregnancy. Taking Strattera or any other medicines during pregnancy should be assessed with caution. The decision to prescribe the medication must be taken by a doctor, taking into account the potential risk to the fetus and the mother. Discuss it with your doctor if you are pregnant or planning a pregnancy.

Possible side effects

This drug has been on the market for more than 20 years. It has been tested to detect the types, severity, and frequency of adverse reactions. Although clinical studies have proved the effectiveness of this treatment method, there are some risks associated with the drug, including:

• The reduction of appetite;
• Stomach discomfort;
• Vomiting;
• Insomnia or early morning wakening;
• Dizziness;
• Mood change;
• Blood pressure increase;
• Urination disorders.

If you experience these or other adverse reactions, they are most likely to be mild and short-term. However, you should contact your doctor to get instructions and additional information.

Strattera: interaction with other drugs

The drug interaction is an alteration of the effects of one drug by the impact of another. Potentially, Strattera can interact with the following drugs and drug classes:

• Ventolin;
• MAO inhibitors;
• Some antidepressants;
• Medicines that can raise blood pressure.

Inform your doctor what other drugs and dietary supplements you are taking to avoid the possibility of drug interaction.

Storage

Keep your medicine in the original packaging until it's time to use it. Store at a temperature not exceeding 30 degrees. Avoid storing in a moist environment. Keep out of reach of pets and children. Follow the instructions if your pharmacist or other health care professional does not tell you the expiration date.

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